PARCC

GENETIC MECHANISMS OF ALDOSTERONE RELATED DISORDERS

TEAM LEADER : Maria-Christina Zennaro

Mail : maria-christina.zennaro@inserm.fr

PHONE : +33 1 53 98 80 42

Localisation : 1st floor, lab 175

DOCTORAL SCHOOL : ED BIO SORBONNE PARIS CITE

Team Awards

Maria-Christina Zennaro

2022 Prix “Etoiles de l’Europe” Ministère de l’Enseignement Supérieur et de la Recherche

2018 “European Medal” of the Society for Endocrinology / British Endocrine society (UK)

2017-20 Training and Research Premium (PEDR) INSERM

2012-16 Scientific Excellence Premium (PEA) Inserm

2014 Richard Underwood PMemorial Visiting Professor – Harvard Medical School, Boston

1999 Futura Stiftung “Award for young South Tyroleans abroad”

1997 Endocrine Society travel award

1997 Award of the French Society of Nephrology

1996 Winner, Searle Young Investigator Award, 22nd International Aldosterone Conference

1994 Award of the Italian Society of Endocrinology

1990 Award of the Italian Society of Internal Medicine

1993 Award of the Italian Society of Hypertension

Sheerazed Boulkroun

2009 Laureate of the Endocrine Trainee Day – Endocrine Society

Fabio Fernandes-Rosa

2021 Award Best Publication in Aldosterone Producing Adenoma field – European Network for the Study of Adrenal tumors (ENS@T) (Nature Genetics 2021)

2018 Jacques Genest Lecturer Award of the Canadian Society of Endocrinology

2018 Award Best Publication in Aldosterone Producing Adenoma field – European Network for the Study of Adrenal tumors (ENS@T) (Nature Genetics 2018)

Alaa Abdellatif

2022 Award Best Publication in Aldosterone Producing Adenoma field – European Network for the Study of Adrenal tumors (ENS@T) (JCEM 2022)

Bakhta Fedlaoui

2022 Young Investigator Award – French Society of Endocrinology

Kelly de Sousa

2020 Award Best Publication in Aldosterone Producing Adenoma field – European Network for the Study of Adrenal tumors (ENS@T) (Hypertension 2020)

Recent Team Funding

International Funding

Horizon Europe (HORIZON) HORIZON-HLTH-2022-TOOL-11: HT-ADVANCE – Imrpoving treatment efficacy in hypertension by biomarker-guided personalised decision support. PI Maria-Christina Zennaro (2023-29)

International SNF-ANR call 2018: GenAdEx – Genetic and molecular contributors to adrenocortical hormone excess. PI Maria-Christina Zennaro (2018-24)

H2020-MSCA-ITN-2020: MINDSHIFT “Mechanistic Integration of vasculature aND endocrine pathways for Subtyping Hypertension: an Inovative network approach for Future generation research Training. Partner Maria Christina Zennaro (2021-2024)

Autonomous Province of Bolzano/Bozen – Call: Research Südtirol/Alto adige 2019 Molecular profiling of uncontrolled and treatment resistant hypertension in the general population: the HyperProfile study. Partner Maria-Christina Zennaro (2020-2022)

Horizon 2020, H2020-PHC-2014-two-stage: ENSAT-HT, Omics-based strategies for improved diagnosis and treatment of endocrine hypertension. PI Maria-Christina Zennaro (2015-21)

Transnational ANR-DFG call 2013 France/Germany: GEA: GEnetic and mechanistic studies of primary Aldosteronism. PI Maria-Christina Zennaro (2014-16)

National Funding

Emergence en recherche 2022 de l’Université paris Cité: Wind3Ms – Role of mineralocorticoid en weight cycling induced metabolic memory and metabolic syndrome. PI Sheerazed Boulkroun (2023-25)

Allocation de Recherche en Endocrinologie – SFE: Nouveaux outils diagnostiques et thérapeutiques dans l’Hyperaldostéronisme Primaire. PI Fabio Fernandes-Rosa (2023-24)

Fondation pour la Recherche Médicale, Program FRM Team 2018: Genetic mechanisms of aldosterone related disorders – Towards integrative precision medicine. PI Maria-Christina Zennaro (2018-23)

ANR Appel à projet 2015: LOCALDO: Mechanisms of local control of aldosterone production in the adrenal gland and their relevance for the pathogenesis of primary aldosteronism (2016-2021). Partner Maria-Christina Zennaro

Fondation pour la Recherche Médicale, Program FRM Teams 2014: Genetic mechanisms of aldosterone related disorders. PI Maria-Christina Zennaro (2015-18)

First call for scientific projects of the University Sorbonne Paris Cité (2013): GLOMeR: Mineralocorticoid receptor activation in glomerular epithelial cells: identification of genomic switches leading to glomerular disease. PI Maria-Christina Zennaro (2014-16)

ANR Blanc 2011: BeyondTASK – Genes and pathways regulating aldosterone production: implications for the pathogenesis of primary aldosteronism. Partner Maria-Christina Zennaro (2012-16)