Le Jeune S , Sadoudi  S, Charue  D , Abid  S, Guigner  JM , Helley  D , Bihan H , Baudry C , Lelong  H , Mirault  T, Vicaut  E , Dhote  R , Mourad  JJ , Boulanger  CM , Blanc-Brude OP. Low grade intravascular hemolysis associates with peripheral nerve injury in type 2 diabetes. PLoS One 2022 Oct 17;17(10):e0275337.  doi: 10.1371/journal.pone.0275337

Poisson J, Tanguy M, Davy H, Camara F, El Mdawar MB, Kheloufi M, Devue C, Lasselin J, Plessier A, Merchant S, Blanc-Brude O, Souyri M, Mougenot N, Dingli F, Loew D, Hatem SN, James C, Villeval JC, Boulanger CM, Rautou PE. Erythrocyte-derived microvesicles induce arterial spasms in JAK2V617F myeloproliferative neoplasm J. Clin. Investigation 2020 May 1; 130(5): 2630–2643 doi: 10.1172/JCI124566;

https://www.youtube.com/watch?time_continue=223&v=9gtF_enENTI&feature=emb_logo

http://www.idf.inserm.fr/actualites/maladies-cardiovasculaires-une-nouvelle-approche-contre-le-syndrome-myeloproliferatif;

Hammoutene A, Biquart L, Lasselin J, Kheloufi M, Tanguy M, Vion AC, Merian J, Colnot N, Loyer X, Tedgui A, Codogno P, Lotersztajn S, Paradis V, Boulanger CM, Rautou PE. A defect in endothelial autophagy occurs in patients with nonalcoholic steatohepatitis and promotes inflammation and fibrosis. J. Hepatology 2020 Mar;72(3):528-538

Merle NS, Grunenwald A, Rajaratnam H, Gnemmi V, Frimat M, Figueres ML, Knockaert S, Bouzekri S, Charue D, Noe R, Robe-Rybkine T, Le-Hoang M, Brinkman N, Gentinetta T, Edler M, Petrillo S, Tolosano E, Miescher S, Le Jeune S, Houillier P, Chauvet S, Rabant M, Dimitrov JD, Fremeaux-Bacchi V, Blanc-Brude OP, Roumenina LT. Intravascular hemolysis activates complement via cell-free heme and heme-loaded microvesicles. JCI Insight. 2018 Jun 21;3(12):e96910. doi: 10.1172/jci.insight.96910. eCollection 2018 Jun 21.

Loyer X, Zlatanova I, Devue C, Yin M, HoWangYin KY, Klaihmon P, Guerin CL, Kheloufi M , Vilar J,  Zannis K, Fleischmann BK, Hwang DW, Park J, Lee H, Menasché P, Silvestre JSS*, Boulanger CM*. Intra-cardiac release of extracellular vesicles shapes inflammation following myocardial infarction. Circulation Res. 2018, 123:100-106 (*Joint last authors )

Vion AC*, Kheloufi M*, Hammoutene A, Poisson J, Lasselin J, Devue C, Pic I, Dupont N, Busse J, Stark K, Lafaurie-Janvore J, Barakat A, Loyer X, Souyri M, Viollet B, Julia P, Tedgui A, Codogno P, Boulanger CM**, Rautou PE**. Autophagy is required for endothelial cell alignment and atheroprotective signaling under physiological blood flow. Proc Natl Acad Sci USA. 2017, 114(41) : E8675-E8684 ;  doi:10.1073/pnas.1702223114 (*Joint first authors ; ** Joint last authors).

Inserm Press Release : http://presse.inserm.fr/en/comment-les-arteres-se-protegent-elles-de-latherosclerose/29553/

Camus S, Moraes JA, Bonnin P, Abbyad P, Le Jeune S, Lionnet F, Loufrani L, Grimaud L, Lambry JC, Charue D, Kiger L, Renard JM, Larroques C, Le Clesiau H, Tedgui A, Bruneval P, Barja-Fidalgo C, Alexandrou A, Tharaux PL, Boulanger CM, Blanc-Brude O.  Circulating Cell Membrane microparticles Transfer Heme to Endothelial Cells and Trigger Vaso-Occlusions in Sickle Cell Disease. Blood 2015 125: 3805-14.

Inserm Press Release: https://presse.inserm.fr/en/red-blood-cell-fragments-attack-blood-vessels/20341/

Selected Review articles

Davidson SM* , Boulanger  CM*, Aikawa E , Lina Badimon, Lucio Barile, Christoph J Binder, Alain Brisson, Edit Buzas, Costanza Emanueli, Felix Jansen, Miroslava Katsur  , Romaric Lacroix , Sai Kiang Lim, Nigel Mackman , Manuel Mayr , Philippe Menasché , Rienk Nieuwland , Susmita Sahoo, Kaloyan Takov   , Thomas Thum , Pieter Vader, Marca H M Wauben, Kenneth Witwer   , Joost P G Sluijter  . Methods for the identification and characterization of extracellular vesicles in cardiovascular studies – from exosomes to microvesicles. Cardiovasc Res 2023 Mar 17;119(1):45-63. doi: 10.1093/cvr/cvac031 

Verweij FJ, Balaj L, Boulanger CM, Carter DRF, Compeer EB, D’Angelo G, El Andaloussi S, Goetz JG, Gross JC, Hyenne V, Krämer-Albers EM, Lai CP, Loyer X, Marki A, Momma S, Nolte-‘t Hoen ENM, Pegtel DM, Peinado H, Raposo G, Rilla K, Tahara H, Théry C, van Royen ME, Vandenbroucke RE, Wehman AM, Witwer K, Wu Z, Wubbolts R, van Niel G.. The power of imaging to understand extracellular vesicle biology in vivo. Nat Methods. 2021 Aug 26, 18(9):1013-1026. doi: 10.1038/s41592-021-01206-3.

Boulanger CM, Loyer X,  Rautou PE, Amabile N. Extracellular vesicles in coronary artery diseases. Nature Rev. Cardiology. 2017 ; 14(5):259-272.. doi: 10.1038/nrcardio.2017.7.