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CV Jean-Sébastien Silvestre

Jean-Sébastien Silvestre

Inserm Research Director (DR1)
TEAM LEADER – REGENERATIVE THERAPIES FOR CARDIAC AND VASCULAR DISEASE
Mail : jean-sebastien.silvestre@inserm.fr
PHONE :+33 1 53 98 80 60


SCIENTIFIC TOPICS

  • Cardiovascular Disease
  • Heart failure
  • Inflammation
  • Non-cell based therapy

  

ITMO

  • Physiopathologie, métabolisme, nutrition

Biosketch

I obtained my PhD in cardiovascular physiology from the University of Paris 7 in 1998. I was then a research fellow at the Institute of Genetic Medicine, University of South California, (Los Angeles, USA) from 1998 till 1999. In 1999, I started my independent research career as an associate professor (Paris-Diderot university) at the Cardiovascular Research Center Inserm Lariboisière (Paris, France). In 2008, I successfully passed the competitive entrance examinations to the National Institute for Health and Medical Research (INSERM) where I was instantly appointed Research Director. In 2009, I moved to the Paris Cardiovascular Research Center – INSERM UMRS 970 (Paris, France) where I am leading a team working on regenerative therapies for cardiac and vascular disease.

 

Academic position

2015: Research director (academic professor level), 1st class (top 20%), INSERM, Paris, France

2008-2014: Research director (academic professor level), 2nd class, INSERM, Paris, France

2006-2008: Honorary member (Junior), Institut Universitaire de France, Paris, France

1999-2008: Associate professor, Paris 7 University, Paris, France

 

 

Responsabilities and activities

 2022-present: Deputy director, Paris Cardiovascular Research Center, Inserm / Université Paris Cité

2022-present: Co-director Graduate School Cardiovascular Sciences – Université Paris Cité, 

https://u-paris.fr/en/cardiovascular-sciences-en/

2021-present: Director, Institut des Sciences Cardiovasculaires – Université Paris Cité,

https://www.institutcardiovasculaireparis.fr/

2019-present: Co-director Master 2 cardiovascular biology (BiVATH), Université Paris Cité

2016-2019:  Program Manager for the French National Research Agency – physiology/pathophysiology

2009-present : Director Team 06-PARCC, Paris, France

 

Awards

2018         Doctoral and Research Supervision award INSERM

2018         Top reviewer award, Arterioscler Thromb Vasc Biol

2017         Jeanne-Philippe Beziat Award, Cardiology, Fondation pour la Recherche Médicale

2014         Award for scientific excellence INSERM

2012         Excellence research chair program, Paris 5 University

2010         Award for scientific excellence INSERM

2007        Excellence research chair program INSERM & Assistance Public – Hôpitaux de Paris

2006        Honorary member – Institut Universitaire de France

2005        French National Research Agency, Young Investigator award

1998         SEARLE young investigator award, Aldosterone conference, New Orleans, USA

Scientific summary

My work focuses on the identification of molecular and cellular mechanisms regulating key events in post-ischemic tissue repair with potent revascularization and regenerative therapeutic promise. Since, 1995, I am a co-author of over 100 original research papers and over 40 reviews or book chapters.