Immune response after pig-to-human kidney xenotransplantation: a multimodal phenotyping study.

Loupy A, Goutaudier V, Giarraputo A, Mezine F, Morgand E, Robin B, Khalil K, Mehta S, Keating B, Dandro A, Certain A, Tharaux PL, Narula N, Tissier R, Giraud S, Hauet T, Pass HI, Sannier A, Wu M, Griesemer A, Ayares D, Tatapudi V, Stern J, Lefaucheur C, Bruneval P, Mangiola M, Montgomery RA.Lancet. 2023 Aug 17:S0140-6736(23)01349-1. doi: 10.1016/S0140-6736(23)01349-1. Online ahead of print.PMID: 37598688

Race-free estimated glomerular filtration rate equation in kidney transplant recipients: development and validation study.

Raynaud M, Al-Awadhi S, Juric I, Divard G, Lombardi Y, Basic-Jukic N, Aubert O, Dubourg L, Masson I, Mariat C, Prié D, Pernin V, Le Quintrec M, Larson TS, Stegall MD, Bikbov B, Ruggenenti P, Mesnard L, Ibrahim HN, Nielsen MB, Matas AJ, Nankivell BJ, Benjamens S, Pol RA, Bakker SJL, Jouven X, Legendre C, Kamar N, Smith BH, Wadei HM, Durrbach A, Vincenti F, Remuzzi G, Lefaucheur C, Bentall AJ, Loupy A. BMJ. 2023 May 31;381:e073654. doi: 10.1136/bmj-2022-073654.PMID: 37257905 

Excess mortality after kidney transplantation: does sex matter?

Truchot A, Raynaud M, Loupy A. Kidney Int. 2023 Jun;103(6):1023-1024. doi: 10.1016/j.kint.2023.03.011.PMID: 37210193

An automated histological classification system for precision diagnostics of kidney allografts.

Yoo D, Goutaudier V, Divard G, Gueguen J, Astor BC, Aubert O, Raynaud M, Demir Z, Hogan J, Weng P, Smith J, Garro R, Warady BA, Zahr RS, Sablik M, Twombley K, Couzi L, Berney T, Boyer O, Duong-Van-Huyen JP, Giral M, Alsadi A, Gourraud PA, Morelon E, Le Quintrec M, Brouard S, Legendre C, Anglicheau D, Villard J, Zhong W, Kamar N, Bestard O, Djamali A, Budde K, Haas M, Lefaucheur C, Rabant M, Loupy A. Nat Med. 2023 May 4. doi: 10.1038/s41591-023-02323-6. Online ahead of print.PMID: 37142762

Machine learning does not outperform traditional statistical modelling for kidney allograft failure prediction.

Truchot A, Raynaud M, Kamar N, Naesens M, Legendre C, Delahousse M, Thaunat O, Buchler M, Crespo M, Linhares K, Orandi BJ, Akalin E, Pujol GS, Silva HT Jr, Gupta G, Segev DL, Jouven X, Bentall AJ, Stegall MD, Lefaucheur C, Aubert O, Loupy A. Kidney Int. 2023 May;103(5):936-948. doi: 10.1016/j.kint.2022.12.011. Epub 2022 Dec 23.PMID: 36572246

Quantitative scoring of progression in transplant glomerulopathy using digital pathology may be superior to Banff cg scoring.

Kikić Ž, Adam BA, Porras AB, Lefaucheur C, Loupy A, Regele H, Cejka D, Haas M, Colvin RB, Mengel M.Kidney Int. 2023 Feb;103(2):365-377. doi: 10.1016/j.kint.2022.10.024. Epub 2022 Nov 25.PMID: 36436680

Outcomes in kidney transplant recipients treated with immediate-release tacrolimus capsules versus extended-release tacrolimus capsules: A cohort study.

Ha YP, Divard G, Mitra N, Putt ME, Pallet N, Loupy A, Anglicheau D, Trofe-Clark J, Legendre C, Bloom RD, Reese PP.Clin Transplant. 2023 Jan;37(1):e14840. doi: 10.1111/ctr.14840. Epub 2022 Nov 27.PMID: 36374204.

Thirty years of the International Banff Classification for Allograft Pathology: the past, present, and future of kidney transplant diagnostics.

Loupy A, Mengel M, Haas M.

Kidney Int. 2022 Apr;101(4):678-691. doi: 10.1016/j.kint.2021.11.028. Epub 2021 Dec 17. PMID: 34922989 

Surrogate Endpoints for Late Kidney Transplantation Failure.

Naesens M, Budde K, Hilbrands L, Oberbauer R, Bellini MI, Glotz D, Grinyó J, Heemann U, Jochmans I, Pengel L, Reinders M, Schneeberger S, Loupy A.

Transpl Int. 2022 May 20;35:10136. doi: 10.3389/ti.2022.10136. eCollection 2022. PMID: 35669974

Allograft Function as Endpoint for Clinical Trials in Kidney Transplantation.

Hilbrands L, Budde K, Bellini MI, Diekmann F, Furian L, Grinyó J, Heemann U, Hesselink DA, Loupy A, Oberbauer R, Pengel L, Reinders M, Schneeberger S, Naesens M.

Transpl Int. 2022 May 20;35:10139. doi: 10.3389/ti.2022.10139. eCollection 2022.

Proposed Definitions of T Cell-Mediated Rejection and Tubulointerstitial Inflammation as Clinical Trial Endpoints in Kidney Transplantation.

Seron D, Rabant M, Becker JU, Roufosse C, Bellini MI, Böhmig GA, Budde K, Diekmann F, Glotz D, Hilbrands L, Loupy A, Oberbauer R, Pengel L, Schneeberger S, Naesens M.

Transpl Int. 2022 May 20;35:10135. doi: 10.3389/ti.2022.10135. eCollection 2022. PMID: 35669975 

New Equations for Estimating the GFR without Race.

Raynaud M, Aubert O, Loupy A.

N Engl J Med. 2022 Apr 28;386(17):1669-1670. doi: 10.1056/NEJMc2119761. PMID: 35476657

mTOR signaling cascade: novel clinical implications in HLA and non-HLA antibody-mediated vasculopathies?

Louis K, Loupy A, Lefaucheur C.Kidney Int. 2022 Mar;101(3):451-454. doi: 10.1016/j.kint.2021.12.008.PMID: 35190030

Data-Driven Chronic Allograft Phenotypes: A Novel and Validated Complement for Histologic Assessment of Kidney Transplant Biopsies.

Vaulet T, Divard G, Thaunat O, Koshy P, Lerut E, Senev A, Aubert O, Van Loon E, Callemeyn J, Emonds MP, Van Craenenbroeck A, De Vusser K, Sprangers B, Rabeyrin M, Dubois V, Kuypers D, De Vos M, Loupy A, De Moor B, Naesens M.

J Am Soc Nephrol. 2022 Nov;33(11):2026-2039. doi: 10.1681/ASN.2022030290. Epub 2022 Sep 7.

Clinical Prediction Model for Antibody-Mediated Rejection: A Strategy to Minimize Surveillance Endomyocardial Biopsies After Heart Transplantation.

Coutance G, Kransdorf E, Aubert O, Bonnet G, Yoo D, Rouvier P, Duong Van Huyen JP, Bruneval P, Taupin JL, Leprince P, Varnous S, Kobashigawa J, Jouven X, Patel J, Loupy A. Circ Heart Fail. 2022 Oct;15(10):e009923. doi: 10.1161/CIRCHEARTFAILURE.122.009923. Epub 2022 Oct 6.PMID: 36200456.

Comparison of artificial intelligence and human-based prediction and stratification of the risk of long-term kidney allograft failure.

Divard G, Raynaud M, Tatapudi VS, Abdalla B, Bailly E, Assayag M, Binois Y, Cohen R, Zhang H, Ulloa C, Linhares K, Tedesco HS, Legendre C, Jouven X, Montgomery RA, Lefaucheur C, Aubert O, Loupy A. Commun Med (Lond). 2022 Nov 23;2(1):150. doi: 10.1038/s43856-022-00201-9.PMID: 36418380.

COVID-19 pandemic and worldwide organ transplantation: a population-based study.

Aubert O, Yoo D, Zielinski D, Cozzi E, Cardillo M, Dürr M, Domínguez-Gil B, Coll E, Da Silva MI, Sallinen V, Lemström K, Midtvedt K, Ulloa C, Immer F, Weissenbacher A, Vallant N, Basic-Jukic N, Tanabe K, Papatheodoridis G, Menoudakou G, Torres M, Soratti C, Hansen Krogh D, Lefaucheur C, Ferreira G, Silva HT Jr, Hartell D, Forsythe J, Mumford L, Reese PP, Kerbaul F, Jacquelinet C, Vogelaar S, Papalois V, Loupy A. Lancet Public Health. 2021 Oct;6(10):e709-e719. doi: 10.1016/S2468-2667(21)00200-0. Epub 2021 Aug 30. PMID: 34474014

Dynamic prediction of renal survival among deeply phenotyped kidney transplant recipients using artificial intelligence: an observational, international, multicohort study.

Raynaud M, Aubert O, Divard G, Reese PP, Kamar N, Yoo D, Chin CS, Bailly É, Buchler M, Ladrière M, Le Quintrec M, Delahousse M, Juric I, Basic-Jukic N, Crespo M, Silva HT Jr, Linhares K, Ribeiro de Castro MC, Soler Pujol G, Empana JP, Ulloa C, Akalin E, Böhmig G, Huang E, Stegall MD, Bentall AJ, Montgomery RA, Jordan SC, Oberbauer R, Segev DL, Friedewald JJ, Jouven X, Legendre C, Lefaucheur C, Loupy A.

Lancet Digit Health. 2021 Dec;3(12):e795-e805. doi: 10.1016/S2589-7500(21)00209-0. Epub 2021 Oct 28. PMID: 34756569 

COVID-19-related medical research: a meta-research and critical appraisal.

Raynaud M, Zhang H, Louis K, Goutaudier V, Wang J, Dubourg Q, Wei Y, Demir Z, Debiais C, Aubert O, Bouatou Y, Lefaucheur C, Jabre P, Liu L, Wang C, Jouven X, Reese P, Empana JP, Loupy A.

BMC Med Res Methodol. 2021 Jan 4;21(1):1. doi: 10.1186/s12874-020-01190-w.

Solid organ procurement and transplantation from deceased donors with vaccine-induced thrombosis and thrombocytopenia.

Loupy A, Goutaudier V, Jacquelinet C, Kerbaul F.Am J Transplant. 2021 Dec;21(12):4098-4101. doi: 10.1111/ajt.16751. Epub 2021 Jul 17.

The emerging field of non-human leukocyte antigen antibodies in transplant medicine and beyond.

Lefaucheur C, Louis K, Philippe A, Loupy A, Coates PT.Kidney Int. 2021 Oct;100(4):787-798. doi: 10.1016/j.kint.2021.04.044. Epub 2021 Jun 26.PMID: 34186057 

Complement inhibition for prevention of antibody-mediated rejection in immunologically high-risk heart allograft recipients.

Patel JK, Coutance G, Loupy A, Dilibero D, Hamilton M, Kittleson M, Kransdorf E, Azarbal B, Seguchi O, Zhang X, Chang D, Geft D, Czer L, Varnous S, Kobashigawa JA.Am J Transplant. 2021 Jul;21(7):2479-2488. doi: 10.1111/ajt.16420. Epub 2021 Feb 11.PMID: 33251691

Statistical performance of 16 posttransplant risk scores in a contemporary cohort of heart transplant recipients.

Coutance G, Kransdorf E, Bonnet G, Loupy A, Kobashigawa J, Patel JK.Am J Transplant. 2021 Feb;21(2):645-656. doi: 10.1111/ajt.16217. Epub 2020 Sep 5.PMID: 32713121 

Data-driven Derivation and Validation of Novel Phenotypes for Acute Kidney Transplant Rejection using Semi-supervised Clustering.

Vaulet T, Divard G, Thaunat O, Lerut E, Senev A, Aubert O, Van Loon E, Callemeyn J, Emonds MP, Van Craenenbroeck A, De Vusser K, Sprangers B, Rabeyrin M, Dubois V, Kuypers D, De Vos M, Loupy A, De Moor B, Naesens M.J Am Soc Nephrol. 2021 May 3;32(5):1084-1096. doi: 10.1681/ASN.2020101418. Epub 2021 Mar 9.PMID: 33687976

Trajectories of glomerular filtration rate and progression to end stage kidney disease after kidney transplantation.

Raynaud M, Aubert O, Reese PP, Bouatou Y, Naesens M, Kamar N, Bailly É, Giral M, Ladrière M, Le Quintrec M, Delahousse M, Juric I, Basic-Jukic N, Gupta G, Akalin E, Yoo D, Chin CS, Proust-Lima C, Böhmig G, Oberbauer R, Stegall MD, Bentall AJ, Jordan SC, Huang E, Glotz D, Legendre C, Montgomery RA, Segev DL, Empana JP, Grams ME, Coresh J, Jouven X, Lefaucheur C, Loupy A. Kidney Int. 2021 Jan;99(1):186-197. doi: 10.1016/j.kint.2020.07.025. Epub 2020 Aug 8.PMID: 32781106

Assessment of the Utility of Kidney Histology as a Basis for Discarding Organs in the United States: A Comparison of International Transplant Practices and Outcomes.

Reese PP, Aubert O, Naesens M, Huang E, Potluri V, Kuypers D, Bouquegneau A, Divard G, Raynaud M, Bouatou Y, Vo A, Glotz D, Legendre C, Lefaucheur C, Jordan S, Empana JP, Jouven X, Loupy A. J Am Soc Nephrol. 2021 Feb;32(2):397-409. doi: 10.1681/ASN.2020040464. Epub 2020 Dec 15.PMID: 33323474 

Application of the iBox prognostication system as a surrogate endpoint in the TRANSFORM randomised controlled trial: proof-of-concept study.

Aubert O, Divard G, Pascual J, Oppenheimer F, Sommerer C, Citterio F, Tedesco H, Chadban S, Henry M, Vincenti F, Srinivas T, Watarai Y, Legendre C, Bernhardt P, Loupy A. BMJ Open. 2021 Oct 7;11(10):e052138. doi: 10.1136/bmjopen-2021-052138.PMID: 34620664 

Impact of the COVID-19 pandemic on publication dynamics and non-COVID-19 research production.

Raynaud M, Goutaudier V, Louis K, Al-Awadhi S, Dubourg Q, Truchot A, Brousse R, Saleh N, Giarraputo A, Debiais C, Demir Z, Certain A, Tacafred F, Cortes-Garcia E, Yanes S, Dagobert J, Naser S, Robin B, Bailly É, Jouven X, Reese PP, Loupy A. BMC Med Res Methodol. 2021 Nov 22;21(1):255. doi: 10.1186/s12874-021-01404-9.PMID: 34809561 

Development and validation of specific post-transplant risk scores according to the circulatory support status at transplant: A UNOS cohort analysis.

Coutance G, Bonnet G, Kransdorf EP, Loupy A, Moriguchi J, Leprince P, Kobashigawa JA, Patel JK.J Heart Lung Transplant. 2021 Oct;40(10):1235-1246. doi: 10.1016/j.healun.2021.06.010. Epub 2021 Jun 24.PMID: 34274182