TEAM LEADER : Eric Tartour
Mail : eric.tartour@aphp.fr
Phone : +33 1 53 98 80 26
Localisation : Lab 177, 1st Floor
Doctoral School : Bio SPC, Université Paris Cité
A synthetic delivery vector for mucosal vaccination.
Billet A*, Hadjerci J*, Tran T*, Kessler P, Ulmer J, Mourier G, Ghazarian M, Gonzalez A, Thai R, Urquia P , Van Baelen AC, Meola A, Fernandez I, Deville-Foillard, MacDonald E, Paolini L, Schmidt F, Rey FA, Kau MS, Tartour E ╪, Servent D╪, Johannes L ╪. Biomaterials. In press * Contributed equally. ╪ co-corresponding author.
Mild dyslipidemia accelerates tumorigenesis through expansion of Ly6Chi monocytes and differentiation to pro-angiogenic myeloid cells.
Tran T, Lavillegrand JR, Lereverend C, Esposito B, Cartier L, Montabord M, Tran-Rajau J, Diedisheim M, Gruel N, Ouguerram K, Paolini L, Lenoir O, Pinteaux E, Brabencova E, Tanchot C, Urquia P, Lehmann-Che J, Le Naour R, Merrouche Y, Stockmann C, Mallat Z, Tedgui A, Ait-Oufella H, Tartour E, Potteaux S. Nat Commun. 2022 14.09 13(1):5399. doi: 10.1038/s41467-022-33034-0.(PMID: 36104342).
Plasma CD27, a surrogate of the intratumoral CD27-CD70 interaction correlates with immunotherapy resistance in renal cell carcinoma.
Benhamouda N, Sam I, Epaillard N, Gey A, Phan L, Pham HP, Gruel N, Saldmann A, Pineau J, Hasan M, Quiniou V, Nevoret C, Verkarre V, Libri V, Mella S, Granier C, Broudin C, Ravel P, De Guillebon E, Mauge L, Helley D, Jabla B, Chaput N, Albiges L, Katsahian S, Adam J, Mejean A, Adotevi O, Vano YA, Oudard S, Tartour E. Clin Cancer Res. 2022 Nov 14;28(22):4983-4994 (PMID: 36067339).
Synergistic effect of combining sunitinib with a peptide-based vaccine in cancer treatment after microenvironment remodeling.
Mougel A, Mejean F, Tran T, Adimi Y, Galy-Fauroux I, Kabore C, Mercier E, Urquia P, Terme M, Tartour E, Tanchot C. Oncoimmunology 2022 Aug 9;11(1):2110218. doi: 10.1080/2162402X.2022.2110218. eCollection (PMID: 35968405).
Synthetic Melanin Acts as Efficient Peptide Carrier in Cancer Vaccine Strategy.
Cuzzubbo S, Roch B, Darrasse-Jèze G, Hosten B, Leclercq M, Vignal N, Banissi C, Tartour E, Carpentier AF. Int J Mol Sci. 2022 Nov 29;23(23):14975. doi: 10.3390/ijms232314975 (PMID: 36499300).
CXCR6 deficiency impairs cancer vaccine efficacy and CD8+resident memory T-cell recruitment in head and neck and lung tumors.
Karaki S, Blanc C, Tran T, Galy-Fauroux I, Mougel A, Dransart E, Anson M, Tanchot C, Paolini L, Gruel N, Gibault L, Lepimpec-Barhes F, Fabre E, Benhamouda N, Badoual C, Damotte D, Donnadieu E, Kobold S, Mami-Chouaib F, Golub R, Johannes L, Tartour E. J Immunother Cancer. 2021 Mar;9(3):e001948. doi: 10.1136/jitc-2020-001948 (PMID: 33692218).
Targeting HGF/c-Met axis decreases circulating regulatory T cells accumulation in gastric cancer patients.
Palle J, Hirsch L, Lapeyre-Prost A, Malka D, Bourhis M, Pernot S, Marcheteau E, Voron T, Castan F, Lacotte A, Benhamouda N, Tanchot C, François E, Ghiringhelli F, de la Fouchardière C, Zaanan A, Tartour E, Taieb J, Terme M. Cancers (Basel). 2021 Nov 5;13(21):5562. doi: 10.3390/cancers13215562 (PMID: 34771724).
Decrease of Pro-Angiogenic Monocytes Predicts Clinical Response to Anti-Angiogenic Treatment in Patients with Metastatic Renal Cell Carcinoma.
Stephane Oudard , Nadine Benhamouda , Bernard Escudier , Patrice Ravel , Thi Tran , Emeline Levionnois , Sylvie Negrier , Philippe Barthelemy , Jean François Berdah , Marine Gross-Goupil , Cora N Sternberg , Petri Bono , Camillo Porta , Ugo De Giorgi , Omi Parikh , Robert Hawkins , Martin Highley , Jochen Wilke , Thomas Decker , Corinne Tanchot , Alain Gey , Magali Terme , Eric Tartour Cells 2021 Dec 22;11(1):17. doi: 10.3390/cells11010017.(PMID: 35011579).
Direct and Indirect Modulation of T Cells by VEGF-A Counteracted by Anti-Angiogenic Treatment.
Bourhis M , Palle J, Galy-Fauroux I , Terme M, Front in Immunol 2021 March 29 12 : DOI : PMID: 33854498 10.3389/fimmu.2021.616837 (PMID 33854498).
Therapeutic Cancer Vaccine and Combinations With Antiangiogenic Therapies and Immune Checkpoint Blockade.
Mougel A, Terme M, Tanchot C Front in Immunol 2019 Mar 14 10 DOI : 10.3389/fimmu.2019.00467 (PMID 30923527).